Hydroquinone Levels in Whitening Body Lotion Circulating in Makassar City by the UV-Vis Spectrophotometry Method
DOI:
https://doi.org/10.33096/pharmrep.v2i2.272Kata Kunci:
Whitening Handbody, Hydroquinone, FeCl₃, UV-Vis SpectrophotometryAbstrak
Hydroquinone is an active compound that is able to control pigment production to inhibit melanin formation and has activity as a skin whitening agent, so hydroquinone is widely used in cosmetic products. Hydroquinone has adverse side effects if used for a long time. BPOM RI has issued a regulation on the prohibition on the use of hydroquinone as a bleach in cosmetics. The purpose of this study was to identify the hydroquinone content in whitening handbody samples circulating in Makassar City and to find out the level of hydroquinone contained in the sample. Qualitative analysis is carried out using FeCl₃ reagents and quantitative analysis using the UV-VIS spectrophotometry method. The number of samples used in this study was as many as 4 samples that did not have a registration number from BPOM RI. The results showed that the 4 samples studied positively contained hydroquinone. The results of the sample test measured at a maximum wavelength of 292 nm, obtained hydroquinone levels at the sample code HB1 = 1.267%; sample code HB2 = 0.912%; sample code HB3 = 0.379% and sample code HB4 = 0.449%.Referensi
Adriani, A. and Safira, R. Analisa Hidrokuinon Dalam Krim Dokter Secara Spektrofotometri UV-Vis. Lantanida Journal, 2018; 6(2): 103-113.
Ariq, M.R., Afriani, K., Zuliandanu, D., Suhartini. Verifikasi Metode Uji Penetapan Kadar Tembaga (Cu) dalam Air Permukaan secara Spektrofotometri Serapan Atom. Warta Akab, 2022; 46(1): 1-6.
BPOM. Temuan Kosmetik Ilegal dan Mengandung Bahan Dilarang/Bahan Berbahaya serta Obat Tradisional Ilegal dan Mengandung Bahan Kimia Obat, BPOM RI, Jakarta, 2018.
BPOM. Peraturan Badan Pengawas Obat dan Makanan Nomor 17 Tahun 2022 Tentang Perubahan Atas Peraturan Badan Pengawas Obat dan Makanan Nomor 23 Tahun 2019 Tentang Persyaratan Teknis Bahan Kosmetika, BPOM RI, Jakarta, 2022.
Estyqomah., Munawarah., Putri, N., Agustina, N.D., Weliyanto, Y., Zuraida. Laporan Praktikum Analisa Obat Makanan dan Kosmetika Analisis Hidrokuinon Pada Handbody Lotion Menggunakan Metode Spektrofotometri UV-Vis. Jurnal Empresi Indonesia, 2022; 1(9):1010-1017.
Faisal, H., Afriadi., Mariska, E. Analisis Kadar Hidrokuinon pada Handbody Lotion Secara Spektrofotometri UV-Vis yang dijual di Kota Medan Tahun 2018. Jurnal Kimia Saintek dan Pendidikan, 2018; 2(2): 76-85.
Fajariyani, A. and Huwaid, M.F. Identifikasi dan Penetapan Kadar Hidrokuinon Pada Kosmetik Krim Pemutih Wajah Dengan Metode Spektrofotometri Uv-Vis. PHRASE Journal, 2022; 2(1):84-94.
Fawwaz M, Muflihunna A, Pratama M, Rahmawati R, Razak R, Baits M. Total phenolic and flavonoid compound of crude and purified extract of green tea leaves (Camellia sinensis) from Makassar-Indonesia. Jurnal Fitofarmaka Indonesia. 2022; 9(3): 19-24.
Fawwaz M, Pratama M, Hasrawati A, Sukmawati, Widiastuti H, Rahmawati. Total carotenoids, antioxidant and anticancer effect of penaeus monodon shells extract. Biointerface Research in Applied Chemistry. 2020; 11(4): 11293-11302.
Feladita, N., Primadiamanti, A. and Juita, M.I. Penetapan Kadar Hidrokuinon Pada Hand Body Lotion Yang Dijual Di Situs Belanja Online Dengan Metode Spektrofotometri UV-Vis. Jurnal Analis Farmasi, 2021; 6(1): 30-36.
Hambali, E., Suryani, A., Rivai, M., Permadi, P. Teknologi Surfaktan dan Aplikasinya, IPB Press, Bogor, 2019.
Putri, A.R and Wahyudiani, M.N. Analisis Kadar Hidrokuinon Pada Krim Pemutih Yang Beredar Di Toko Online Dengan Metode Spektrofotometri. Jurnal Sosial dan Sains, 2021; 1(11): 1464-1471.
Rahmadari, D.H., Ananto, A.D. and Juliantoni, Y. Analisis Kandungan Hidrokuinon dan Merkuri Dalam Krim Kecantikan Yang Beredar Di Kecamatan Alas. Jurnal Kimia & Pendidikan Kimia, 2021; 3(1): 64-74
Suharyani, I., Karlina, N., Rahmi, N., Salsabila, D.Z., Annisa, N., Sadira, A., Astuti, S.Y., Rahmasari, Y. Review : Analisis Kualitatif dan Kuantitatif Hidrokuinon Dalam Sediaan Kosmetika, Journal of Pharmacopolium, 2021; 4(3): 162-173.
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